Icy conditions and a spate of road traffic collisions before dawn today (Monday 19 January) led to the A24 being closed between the Washington and Ashington roundabouts until 7.15am.
At around 6am a van left the northbound carriageway and overturned near to the Orchard Fisheries and Spring Gardens, blocking the road.
Its occupants, a 29-year-old man and a 25-year-old man, sustained arm and facial injuries and were taken to hospital by ambulance.
Elsewhere in the same area at least seven vehicles were reported to have slid off the road, leading to it being closed both north and southbound and diversions being set up via Ashington.for more than an hour..
Motorists in Sussex generally are being advised to take extra care while freezing temperatures persist.